New CRISPR Technique Selectively Shreds Cancer Cells, Including “Undruggable” Cancers - Innovative Genomics Institute (IGI)

After two days of experience with Claude Fable 5 I think the best way to describe it is relentlessly proactive. It knows a whole lot of tricks and it will …

Running Gemma 4 26B-A4B and Qwen3.6 35B-A3B locally with llama.cpp, MTP speculative decoding, multimodal support, and PI as a coding agent.

Can ChatGPT replace translators? A freelance translator shares a funny Ottawa story about AI translation, professional judgment and why human expertise still matters.

We’re on a journey to advance and democratize artificial intelligence through open source and open science.

NEW: malware developers added nuclear & biological weapons text to to their spyware.

Goal? To trigger LLM safety refusals... so that their spyware wouldn't be analyzed by an AI security scanner.

Cleanest practical example I can think of for why over-indexing on first order https://t.co/WLxe0LWo8s

Peter Thiel-chaired data intelligence group sued publication over reports that Switzerland rejected its approaches

The FCC is proposing to require KYC for anyone who uses a phone. We can act now to stop further erosion of our privacy.

Last Updated: 2026-06-12T04:22:42Z (UTC) What’s Happening It appears a new AUR package maintainer (arojas) adopted and infected 408+ packages. The compromise was reported and other AUR maintainers have been working to remove the infected packages. The affected packages were modified with preinstall scripts to use npm to install the atomic-lockfile package, a malicious payload. Here’s an example of the change: This blog has a deep dive into the attack. Actions If you don’t use Arch (b...

depthfirst

About a year ago I wrote on this blog about how coding with LLMs would not work for me, even if there were no ethical or environmental concerns preventing me to use them. I'm not going to repeat the…

In a voice vote earlier this week, the House of Representatives passed H.R. 6028, the “Legislative Branch Agencies Clarification Act.” The legislation is presented as a technical reorganization of some government agencies, but it’s much more than that. H.R. 6028 would fundamentally change the U.S....

WASI 0.3.0
WASI 0.3 is official, and async is now native to WebAssembly Components. The WASI Subgroup voted to ratify WASI 0.3.0, rebasing WASI onto the WebAssembly Component Model's async primitiv...

‘There was no animation software in those days. So I videotaped my brother David running, jumping and climbing in a car park’

The US House reading Dutch emails shows digital sovereignty is about who can access data, not just where it is stored.

As AI starts reading and actioning our inboxes, email authentication becomes the trust layer that the future of email depends on.

The advance in fabric technology comes alongside a new benchmark for atmospheric water harvesting.

A university professor on what we lose when we lose the book as a physical medium.

An idea for PDFs that render normally for humans while exposing clean markdown structure to extractors and LLMs in the same file.

A tour of erm, a local CLI that removes disfluencies from English speech recordings using faster-whisper, a few detectors that look at the audio directly, and ffmpeg.

We present MaxProof, a population-level test-time scaling framework for competition-level mathematical proof in the MiniMax-M3 series. M3 first trains three proof-oriented capabilities -- proof generation, proof verification, and critique-conditioned proof repair -- using a defense-in-depth generative verifier engineered for low false-positive rate. These capabilities are merged into a single released M3 model. At test time, MaxProof treats the model as a generator, verifier, refiner, and ranker, searches over a population of candidate proofs, and returns one final proof through tournament selection. With MaxProof test-time scaling, the M3 model reaches 35/42 on IMO 2025 and 36/42 on USAMO 2026, exceeding the human gold-medal threshold on both.

Postgres 19 brings native temporal table support. Shaun Thomas covers WITHOUT OVERLAPS, FOR PORTION OF, and temporal foreign keys - and what's still missing.