Ask HN: How you manage local long lived research projects and LLM's?

I was kind of inspired by this hacker news article where someone collected data to solve their fatigue problem: https://news.ycombinator.com/item?id=48605117

A similar but smaller I did was to collect nut-free restaurants to eat in Chicago. So I had articles, reviews, emails, phone calls, all sorts of stuff. I found it very easy to just use Copilot as my interface and I just data into it over and over and asked it to organize it.

https://github.com/joshuabremer/chicago-allergy-eats

This seems like a common thing where people would be working on a longer-term research or data collection task where you use the LLM to answer questions or help you accept the data. Does anyone have a standard format for this? Or an example that is working for you?